• DMG supports the production of hormones, antibodies, neurotransmitters, amino acids, and other essential substances in the body. DMG does not suppress or excite the immune system. Instead, it is an immune modulator. One of the most remarkable properties of DMG is that it can be used with other nutrients to create truly comprehensive formulas.
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Dimethylglycine, also known as DMG, is a natural substance found in both plant and animal cells, and is derived from the amino acid glycine (see reference 1 under Clinical Summary para 1). As a supplement, it is purported to offer a number of health benefits, from enhancing physical performance to improving behavior in children with autism and attention deficit disorder. However, the evidence to support these claims is lacking, according to the Memorial Sloan Kettering Cancer Center (see reference 1 under Mechanism of Action).

How DMG Works

The body produces DMG in the cells by breaking down choline (see reference 1 under Clinical Summary). In the body, it acts as an antioxidant and improves oxygenation of the cells (see reference 1 under Clinical Summary). The thought is that taking DMG as a supplement may further enhance oxygenation, which improves athletic performance (see reference 1 under Clinical Summary). It is also thought to act as a neurological stimulator, which is why it has gained popularity in the autism community (see reference 1 under Clinical Summary). According to an October 2009 review article on the use of complementary medicine in autism published in 'Child and Adolescent Psychiatric Clinics,' the two clinical trials testing the use of DMG on children with autism showed no positive effect or improvement in behavior (see reference 2 under DMG).

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Safety Concerns

DMG is considered a safe and non-toxic substance, according to MSKCC (see reference 1 under Clinical Summary). If you're supplementing your diet with DMG, be sure to inform your doctor to monitor for any potential side effects or interactions. Additionally, while it's safe to take DMG, do not rely on it as a cure or treatment for any illness.

By Ashley Watson

At VetriScience^® Laboratories, we take pride in our unique supplements and our use of pure and highly researched ingredients in products that are safe, effective, and developed by vets for vets. Our research on a few different signature ingredients has helped build our reputation as a leader in the animal health industry. One of these is our Glyco FLEX^® line of supplements, all of which feature Perna canaliculus (GlycOmega™ brand) green-lipped mussel from New Zealand, as well as our flagship ingredient: N,N-Dimethylglycine (DMG). In fact, DMG is included in a large percentage of our products because of its comprehensive properties. Because we want to ensure that vets understand the full benefits of DMG, this week’s blog post will cover its history and function.

History of DMG

Interestingly, DMG supplement use began with horses. It was used to support performance and endurance in our equine companions for years, and then we realized what DMG had many other condition specific properties. Our parent company, FoodScience^® Corporation, has received five U.S. patents due to our extensive research on this vital nutrient. Today, the manual of nutritional supplementation, Prescription for Nutritional Healing, recommends DMG for support of over 40 different health conditions.

Basic Facts About DMG

DMG is a naturally occurring amino acid derivative and a methyl donor that supports the body’s metabolic processes.

As an immune system modulator, DMG supports circulation, oxygen utilization, brain health, liver health, cellular structure, cardiovascular health, as well as joint comfort and hydration.

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DMG supports the production of hormones, antibodies, neurotransmitters, amino acids, and other essential substances in the body.

DMG does not suppress or excite the immune system. Instead, it is an immune modulator.

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One of the most remarkable properties of DMG is that it can be used with other nutrients to create truly comprehensive formulas. We carry a wide variety of condition specific products that feature DMG. Products designed for liver support, immune support, and geriatric animal health are some of our most well-known DMG supplements.

Liver Health and Cognitive Function

Because DMG supports the production of a host of beneficial substances, including glutathione, it supports the liver in the detoxification process. That’s partly why it is included in Vetri Liver Canine, which supports Phase II detoxification, which removes unwanted substances from the body by converting them into water-soluble chemicals that can be easily excreted via bile and urine. Glutathione, cysteine, turmeric, and DMG found in Vetri Liver Canine work together to support the liver in this process. We also offer Vetri Liver Feline.

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In addition to liver health, healthy circulation is a huge piece of maintaining joint health and comfort throughout life. Magiciso. Healthy circulation and oxygen utilization also support neurological health, so that DMG has earned a reputation as a supporter of social skills, cognitive function, and balanced mood states.

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Immune Health in Geriatric Animals

DMG is wildly versatile and unique, which is one of the main reasons we have included it in so many of our products. Aside from our joint health products, our immune support products and supplements for geriatric dogs and cats are some of our most sought after supplements. Vetri DMG™ is a formula to support immune system health and function in dogs and cats. This high potency formula is perfect for aging pets since DMG helps to strengthen the immune response when the body is confronted by foreign antigens, microorganisms, and stress, all of which have a larger impact on older dogs and cats.

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If you are looking for overall support in senior dogs, Canine Plus™ Senior is a geriatric formulation with a complete foundation for senior dogs in a bite-sized chew. Canine Plus™ features DMG, CoQ10, EPA, DHA, L-taurine, L-glutamine, phosphatidylserine, alpha lipoic acid, grape seed extract, milk thistle extract, and bilberry extract to support cardiovascular, liver, cognitive, eye, joint, and digestive functions, as well as maintain the physical and mental well-being of senior dogs. Nu Cat™ Senior also features DMG, and it is specifically formulated for geriatric cats.

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If you have any questions about the many benefits and properties of our DMG supplements, please don’t hesitate to contact us.