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League Of Legends Attack Dmg Runes Or Lethality On Adc Build

It looks like you're doing the armor penetration math right.
There are websites out there that let you calculate the actual DPS increase with varying runes, masteries, items, and even buffs - I'd recommend trying to find such a site to answer that kind of question. It really depends on the AD score's your buffing and the armor of the champions you are striking as well.
But if you penetrate exactly the same amount of armor as a target has it's pretty easy, as you just increased your DPS by the same percentage. A target with 100 armor reduces damage taken by 100, the inverse of which is increasing your DPS by 100. If you have 30 armor penetration and smack a target with 30 armor, that's 30% more damage. With AD it's all about how much you already have. Most champions start with ~50 and ramp that up to ~110 from leveling up.
What is better largely depends on what your acquiring. You get attack damage (~3.5) with each level up, but you get 0 armor penetration from each level up (unless you place skill ranks into something that generates it). It's also generally easier to add AD into any build than armor penetration, so you generally have to by trying, rather hard, to get armor penetration (especially in runes) to increase your DPS at a lower rate than AD.
The only thing to keep in mind there is how skills interact with such attributes. Riven can convert AD into a pretty swanky shield for instance - which doesn't benefit at all from armor penetration.
If you want to get really into it the formulas for determining the damage reduction for armor and magic resistance are as fallows, were X represents your armor or magic resistance:
X/(100+X) = %damage reduction
100/(100+X) = %damage taken
But anyways, I've generally found Armor Penetration runes to be more effective than attack damage runes for increasing your DPS against other champions. If you're mostly farming minions flat AD tends to be better, as minions essentially don't have any armor or magic resistance to penetrate.

League Of Legends Attack Dmg Runes Or Lethality On Adc 1

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